What Mastic Gum Is
Mastic gum is the dried resin of Pistacia lentiscus, a Mediterranean shrub in the same family as pistachio and cashew. The Chios variety, var. chia, is the one used in almost every clinical trial. Remedy's Mastic Gum supplies 1000 mg of powdered resin per vegan capsule, with 60 capsules per bottle.
It is best known for H. pylori and best supported for indigestion, and this page states both honestly.
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1000 mg per capsule: Single-ingredient mastic resin.
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60 capsules: Two months at 1 daily.
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EMA range: 1 to 2 g a day for mild dyspepsia.
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Traditional use: Stomach complaints and breath, for about 2,500 years.
The full evidence map is in our mastic gum overview.
Supplement Facts
Serving size: 1 Vegan Capsule. Servings per container: 60.
| Amount Per Serving |
Amount |
% Daily Value |
| Mastic gum resin (Pistacia lentiscus) |
1000 mg |
* |
* Daily Value not established.
Other ingredients: Cellulose, Glycerin, Water (vegan capsule)
Directions: One capsule daily, with food or without.
Made in the USA.
What the Evidence Actually Shows
Rather than print a benefits list, we would rather print the shape of the literature. These counts came off PubMed on 18 September 2026 and anyone can rerun them.
| What PubMed holds on mastic gum |
Count |
| All records on mastic gum or Pistacia lentiscus |
537 |
| Records tagged as human |
169 |
| Randomized or clinical trials, every topic |
30 |
| Systematic reviews or meta-analyses |
3 |
| Records mentioning H. pylori |
22 |
| Records mentioning SIBO |
0 |
Mastic has a lot of laboratory work and a thin layer of human trials, and the trials do not all point the way the marketing does.
The H. pylori Question
This is the claim mastic is sold on most often, so it gets the numbers rather than a slogan.
| Arm of the 2010 randomized pilot |
H. pylori cleared |
| Mastic 350 mg, 3 times a day, 14 days |
4 of 13 |
| Mastic 1.05 g, 3 times a day, 14 days |
5 of 13 |
| Mastic 350 mg plus pantoprazole, 14 days |
0 of 13 |
| Pantoprazole plus 2 antibiotics, 10 days |
10 of 13 |
In the 2010 randomized pilot, mastic alone cleared the infection in 4 or 5 of 13 patients, against 10 of 13 on standard triple therapy.[1]The effect of mastic gum on Helicobacter pylori: a randomized pilot study — Phytomedicine (2010) View source A 2003 study at 4 g a day cleared 0 of 8.[2]Mastic gum has no effect on Helicobacter pylori load in vivo — Journal of Antimicrobial Chemotherapy (2003) View source Mastic is not a replacement for antibiotics, and we do not sell it as one. The detail is in mastic gum and H. pylori.
Where It Did Best: Indigestion
The strongest human result is in functional dyspepsia, meaning recurring indigestion with no ulcer or other cause found.
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Trial: 148 patients, randomized and double-blind against placebo.
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Dose: 350 mg 3 times a day for 3 weeks.
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Result: Marked improvement in 77% on mastic and 40% on placebo.
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Replicated: A 2025 crossover trial at 1.4 g a day, against no treatment.
Stomach pain, dull upper abdominal ache and heartburn were among the symptoms that improved.[3]Is Chios mastic gum effective in the treatment of functional dyspepsia? A prospective randomised double-blind placebo controlled trial — Journal of Ethnopharmacology (2010) View source The European Medicines Agency accepts mastic as a traditional herbal medicine for mild dyspeptic disorders.[4]European Union herbal monograph on Pistacia lentiscus L., resina (mastic) — European Medicines Agency View source More in mastic gum for functional dyspepsia.
Chewing Gum or Capsule
The form decides where mastic acts, which decides which studies apply to it.
| Form |
Where it acts |
What the evidence used it for |
| Raw tears or chewing gum |
Mouth |
Plaque and saliva bacteria |
| Toothpaste |
Mouth |
Bad breath, 1 trial |
| Capsules or powder |
Stomach |
Dyspepsia and H. pylori trials |
The plaque and breath studies used chewing gum or toothpaste, so they say nothing about a swallowed capsule. See mastic gum for teeth and oral health and Chios mastic gum, chewing gum vs capsules.
How to Use It
The European Medicines Agency range is the sensible anchor, because it is the only official dose there is.
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Our label: 1 capsule, 1 g, once a day.
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EMA range: 0.5 to 1 g twice daily, 1 to 2 g in total.
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Review point: See a doctor if indigestion lasts beyond 2 weeks.
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Timing: No trial compared timing or food, so either is fine.
Higher doses were used in H. pylori studies without better results. Where mastic fits alongside other gut claims, including SIBO, is in mastic gum for SIBO.
Safety and Allergy
In trials mastic was well tolerated, and the EMA monograph lists no known undesirable effects and no reported interactions. Allergy is the real caution.
| Situation |
Position |
| Allergic to Mastisol adhesive, pistachio, cashew or tree resins |
Avoid unless cleared by an allergist |
| Pregnant or breastfeeding |
Not recommended by the EMA |
| Under 18 |
Not recommended by the EMA |
| Diagnosed H. pylori or ulcer |
Prescribed treatment first, then discuss |
| Indigestion beyond 2 weeks, weight loss or vomiting |
See a doctor |
Among 18 people allergic to Mastisol, a surgical skin adhesive that contains mastic, 13 reacted to gum mastic on patch testing.[5]Contact Dermatitis From Gum Mastic (Pistacia lentiscus) and Gum Storax (Liquidambar styraciflua) in Mastisol-Allergic Patients — Dermatitis (2021) View source The full list is in mastic gum side effects and allergy.
Why Choose Remedy's Mastic Gum
No trial makes one mastic capsule better than another, so the honest differentiators are the amount and what the page is willing to say.
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1000 mg: 1 capsule sits at the low end of the EMA range.
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Single ingredient: Mastic resin, with 0 other actives.
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No eradication claim: Because the H. pylori trials do not support one.
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No origin claim we cannot back: The label states the amount, not a PDO name.
Two months per bottle at 1 capsule a day, with the evidence and its limits printed on the page rather than left out.
Frequently Asked Questions
What is mastic gum? +
The dried resin of Pistacia lentiscus, a shrub in the pistachio family. Each capsule holds 1000 mg of it.
Does mastic gum get rid of H. pylori? +
Not reliably. In the best trial it cleared 4 or 5 of 13 patients, against 10 of 13 on triple therapy.
Does mastic gum help indigestion? +
In 148 patients with functional dyspepsia, 77% improved on mastic against 40% on placebo over 3 weeks.
How much mastic gum should I take? +
Our label is 1 capsule, 1 g, daily. The EMA range for mild dyspepsia is 1 to 2 g a day.
How long does 1 bottle last? +
Sixty capsules is 2 months at 1 capsule a day, or 1 month at 2 a day.
Can mastic gum help GERD? +
No trial has tested it in GERD. Heartburn improved as 1 symptom of functional dyspepsia in 2 trials.
What are the side effects of mastic gum? +
The EMA lists 0 known undesirable effects. Allergy is the main risk, especially with a Mastisol adhesive allergy.
Is mastic gum safe in pregnancy? +
Safety has not been established, so the EMA does not recommend it in pregnancy or breastfeeding, or under 18.
Is this Chios PDO mastic? +
The label states 1000 mg of mastic resin and does not carry the PDO name Masticha Chiou, registered in 1997.
Should I chew it or swallow it? +
Swallow the capsule. The oral studies used chewing gum, while the stomach trials used about 1 g swallowed.
Does mastic gum help SIBO? +
It has never been studied for SIBO. PubMed returns 0 records for mastic and small intestinal bacterial overgrowth.
Should I take it with food? +
Either is fine. 0 trials compared timing or food, so our label allows both.
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