A man at his kitchen table looking thoughtfully at a plain supplement bottle

Brian Steinblock

Selenium and Diabetes Risk: An Open Question Worth Knowing

Selenium is involved in glucose metabolism, which at first hearing sounds like straightforwardly good news. Then you read what 1 pooled analysis of randomized trials set out to test in...

A woman cracking Brazil nuts with a nutcracker at her kitchen table

Vladimir Primak

Selenium Deficiency and Food Sources: Why Soil Decides

Selenium is 1 of maybe 2 nutrients where the amount in your food depends on the soil. It depends on where the food grew rather than on the food itself....

A woman holding a multivitamin and a selenium bottle, checking one before the other

Maria Lentz

Selenium Dosage: 55, 200 and 400 Micrograms Explained

With most supplements the dosage question is entirely about getting enough of the thing, and 55 mcg would settle it. With selenium the 400 mcg ceiling matters more. The gap...

A man in his sixties reading a newspaper in an armchair with tea and a plain supplement bottle

Gene C Lentz

Selenium and Prostate Cancer: What the SELECT Trial Found

For 2 decades selenium was sold on cancer prevention, and the reasoning came from real epidemiology. Then 1 randomized trial tested it directly. SELECT found no reduction in prostate cancer...

A man counting a multivitamin, a selenium bottle and a bowl of Brazil nuts on his counter

Brian Steinblock

Selenium Side Effects and Toxicity: The Narrowest Window on the Shelf

Most supplement safety sections you will read online are precautionary boilerplate that almost nobody actually needs. Selenium is 1 of maybe 3 where the ceiling is close enough to matter....

A woman talking with a clinician across a plain desk in a consulting room

Maria Lentz

Selenium and Thyroid Health: Two Reviews, Opposite Answers

Selenium is required to convert thyroid hormone into its active form, which makes the claim reasonable. Then 2 meta-analyses landed 1 year apart and disagreed. One found insufficient evidence. The...

A woman at her kitchen table holding a Brazil nut beside a plain supplement bottle

Gene C Lentz

What Is Selenium? Benefits, Evidence, and the Narrow Window

Selenium is not short of evidence at all, and it has 1289 clinical trials standing behind it. There are also 539 meta-analyses, more than almost anything else on these shelves....

Calm oak-table still life with a white jar of capsules, Griffonia seeds, a seed pod and a blank notebook

Vladimir Primak

Was 5-HTP Ever Banned? The 1989 Story, Corrected

Why is 5-HTP banned is a live search question with a short answer that almost nobody gives. It is not banned, it never was, and the confusion has 1 source....

Row of plain white bottles on an oak shelf with a jar of cream capsules set apart at the far end

Gene C Lentz

5-HTP Side Effects and Drug Interactions

The 4 most common wordings of a live search question about 5-HTP all ask the same thing. They ask what you must not mix it with. The answer is 8...

Overhead view of a white jar, one cream capsule on a dish, a glass of water and a plain pill organiser

Maria Lentz

5-HTP Dosage and Timing

There is no established dose of 5-HTP, and the honest way to answer the question is to list what the trials actually used. They used 3 different amounts. The most...

Sunlit oak table with a steaming mug of tea, dried grasses and a plain white supplement jar

Gene C Lentz

The clearest positive anxiety result for 5-HTP came from 1 study that also included 24 healthy volunteers. In those healthy volunteers it did nothing. It significantly reduced an experimental panic...

Three white dishes in a row holding cream capsules, plain white tablets and pale powder for comparison

Vladimir Primak

5-HTP vs Melatonin and L-Tryptophan

Tryptophan, 5-HTP and melatonin are 3 points on a single chain rather than 3 competing products. Knowing the order explains most of the differences. Tryptophan becomes 5-HTP, 5-HTP becomes serotonin,...

Vitamins

Selenium and Diabetes Risk: An Open Question Worth Knowing

Selenium Deficiency and Food Sources: Why Soil Decides

Selenium Dosage: 55, 200 and 400 Micrograms Explained

Selenium and Prostate Cancer: What the SELECT Trial Found

Selenium Side Effects and Toxicity: The Narrowest Window on the Shelf

Selenium and Thyroid Health: Two Reviews, Opposite Answers

What Is Selenium? Benefits, Evidence, and the Narrow Window

Was 5-HTP Ever Banned? The 1989 Story, Corrected

5-HTP Side Effects and Drug Interactions

5-HTP Dosage and Timing

5-HTP for Anxiety and Mood

5-HTP vs Melatonin and L-Tryptophan

Vitamins

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