Quick Answer: Deep Sleep Tincture
Sleep tincture is a concentrated liquid blend of valerian, hops, passionflower, and related sedative herbs that shortens sleep onset by 15 to 20 minutes and improves sleep quality. Take 2 to 3 mL (40 to 60 drops) sublingually 30 to 60 minutes before bed. Each 2 fl oz bottle holds 30 servings.
What Is Deep Sleep Tincture?
Deep Sleep Tincture is a multi-herb liquid extract designed to support sleep onset, depth, and continuity through 3 GABA-active mechanisms. The blend pairs valerian (Valeriana officinalis), hops (Humulus lupulus), and passionflower (Passiflora incarnata) in a 40 to 50% food-grade alcohol base. Each 2 mL dropperful from a 2 fl oz bottle delivers a clinically meaningful dose in roughly 30 servings.
- Valerenic acid
- The signature compound in valerian root. Modulates GABA-A receptors and shortens sleep latency by 15 to 20 minutes vs placebo across 16 RCTs (n=1,093).
- Humulones
- Bitter acids in hops cones with mild sedative-hypnotic activity. Hops + valerian combinations show enhanced sleep effects vs valerian alone in 7 trials.
- Passionflower (chrysin)
- Apigenin and chrysin are the GABA-active flavonoids in Passiflora incarnata. 4 RCTs show modest sleep-quality improvements at 250 to 500 mg dried herb equivalents.
- Sleep latency
- The time from lights-out to first stable sleep stage. Healthy sleep latency is 10 to 20 minutes. Insomniacs typically take 30+ minutes; valerian shortens this by 15 to 20 minutes on average.
- Sleep architecture
- The pattern of REM, non-REM stages 1 to 3, and deep sleep across the night. Most herbal sleep aids improve sleep onset and quality without significantly altering architecture, unlike Z-drugs.
Deep Sleep Tincture Benefits: Clinical Evidence
The 3-herb blend draws on independent trial data for each ingredient totaling 1,400+ participants across 23 RCTs.
| Benefit |
Clinical Finding |
Trial Dose |
| Sleep onset (latency) |
Valerian shortened sleep latency 15 to 20 min vs placebo across 16 RCTs (n=1,093)1
|
400 to 900 mg pre-bed |
| Sleep quality (subjective) |
Hops + valerian improved subjective quality in 4 of 7 trials |
187 mg valerian + 41 mg hops |
| Anxiety + sleep |
Passionflower improved insomnia secondary to anxiety in 4 RCTs (n=185) |
500 mg dried herb / day |
| Wake after sleep onset |
Valerian reduced WASO 12 minutes vs placebo (subjective measure) |
600 to 900 mg pre-bed |
| No next-day grogginess |
Unlike Z-drugs, valerian-based formulas show no significant residual sedation in 11 of 14 measured trials |
Standard pre-bed protocols |
References: Bent 2006 valerian meta-analysis, NCCIH valerian overview, Ngan 2011 passionflower sleep RCT.
What Tincture Is Best for Sleep?
The best sleep tincture depends on your specific issue. For sleep onset, valerian-led formulas like Deep Sleep work best. For pain-driven sleep disturbance, our Jamaican dogwood sleep aid is more appropriate. For anxiety-driven insomnia, kava blends help most. The table compares the 3 main herbal sleep approaches.
| Sleep Issue |
Best Herbal Approach |
Effect Onset |
| Trouble falling asleep |
Valerian-led blend (Deep Sleep) |
30 to 60 min |
| Anxiety-driven insomnia |
Kava + valerian blend |
15 to 30 min |
| Pain disrupting sleep |
Jamaican dogwood |
30 to 60 min |
| Frequent night waking |
Hops + passionflower |
30 to 90 min |
| Cortisol-driven (3 AM wake) |
Ashwagandha (multi-week) |
4 to 8 weeks |
Read the full deep restful sleep tinctures roundup for side-by-side comparisons.
Sleep Tincture for Insomnia and Anxiety
For anxiety-driven insomnia, the passionflower component plus mild valerian sedation usually addresses both. For pure insomnia (no anxiety), valerian and hops do the heavy lifting. Most users notice sleep-onset improvement within 1 to 7 nights and continued improvement over 2 to 4 weeks.
For dedicated anxiety formulas see anxiety tinctures roundup. To craft a blended sleep mix at home, see the calming blend recipe.
Strongest Herbs for Sleep
Among the herbs in the GABA-modulating category, the relative potency is roughly: Jamaican dogwood > valerian > hops > passionflower > chamomile, by sedative effect. Our Deep Sleep formula is balanced for general use; users with severe insomnia may benefit from the more potent Jamaican dogwood single-herb option, used carefully under practitioner guidance.
How to Use Deep Sleep Tincture
Squeeze 2 to 3 mL (40 to 60 drops) under the tongue 30 to 60 minutes before bed. Hold the dose under the tongue for 30 to 60 seconds, then swallow. For users sensitive to taste, dilute the dose in 2 to 4 oz of warm water or chamomile tea — sublingual onset is preserved if held first.
-
Standard dose: 2 mL 45 minutes before lights-out.
-
Severe insomnia (with practitioner): 3 mL 30 to 60 minutes before bed.
-
Sensitive users: 1 mL for the first 3 nights, then scale up.
-
Maximum: 4 mL per evening dose. Do not exceed 30 nights consecutive use.
Pair with sleep hygiene: dim lights 1 hour before bed, no screens 30 minutes before, and a cool 65 to 68°F bedroom for best results.
Deep Sleep Tincture Dosage
Across 16 randomized trials of valerian (n=1,093), sleep onset shortened by 15 to 20 minutes vs placebo, with no significant next-day grogginess in 11 of 14 measured outcomes — a clean efficacy profile vs prescription Z-drugs.
| Goal |
Suggested Dose |
Timing |
Duration |
| Trouble falling asleep |
2 mL (40 drops) |
30 to 45 min pre-bed |
2 to 4 weeks per cycle |
| Severe insomnia (occasional) |
3 mL (60 drops) |
45 to 60 min pre-bed |
Up to 14 nights |
| Anxiety + insomnia |
2 mL evening + 1 mL afternoon |
2 doses spaced 6 hr apart |
4 to 6 weeks |
| Sensitive first-time users |
1 mL |
30 min pre-bed |
3 nights to test |
| Maximum daily |
4 mL |
Single evening dose |
Cycle 4 wks on / 1 wk off |
For detailed dose translation across formats see beginner dosage guide.
Why Choose Remedy’s Nutrition® Deep Sleep Tincture
| What You Get |
Why It Matters |
| 3 GABA-active herbs |
Multi-mechanism approach. Each herb targets a different GABA receptor pathway. |
| 1:2 herb-to-solvent ratio |
2 to 3x more concentrated than 1:5 retail tinctures. Smaller dose, faster effect. |
| 12-week steeping process |
Most commercial tinctures steep 2 to 4 weeks. Our 12-week process extracts more valerenic acid. |
| Hand-formulated, small batch |
Made in Key Largo, Florida since 1972 by certified herbalists. |
| Zero fillers, dyes, sweeteners, melatonin |
Just the herbs and food-grade alcohol. No synthetic melatonin, no GABA powder, no L-theanine. |
| Third-party tested |
Each batch tested for valerenic acid potency, microbial safety, heavy metals. |
| 30-day satisfaction guarantee |
Risk-free trial. Full refund if not satisfied. |
Who Deep Sleep Tincture Helps Most
Best for adults who fall asleep slowly (latency over 30 minutes), wake unrefreshed, or want a non-prescription option without melatonin. Less suited for severe chronic insomnia (consult sleep medicine), pain-driven insomnia (try Jamaican dogwood), or sleep apnea (treat the root cause first). For broader category framing see complete tincture buying guide.
Limitations of the Evidence
Effect sizes for valerian and hops are real but modest — 15 to 20 minutes faster sleep onset is meaningful but not dramatic compared to prescription sedatives. Most published trials run only 2 to 6 weeks; long-term sleep-architecture data is limited. About 1 in 5 users see no measurable change after 14 nights — non-responders should explore other categories rather than escalating dose. The exact 3-herb combination in Deep Sleep has not been tested in a published RCT; effects are inferred from each component’s monograph evidence.
Safety, Interactions & Contraindications
Important sedation caution. Do not drive or operate machinery within 6 hours of dosing until you know your response. Do not combine with prescription sedatives, opioids, alcohol, or muscle relaxants. Stop 14 days before scheduled surgery.
| Consideration |
Action |
| CNS depressants |
Synergistic with benzodiazepines, opioids, Z-drugs, alcohol. Do not combine. |
| Pregnancy and breastfeeding |
Insufficient data. Avoid — valerian and hops both lack pregnancy safety studies. |
| Driving and machinery |
Do not operate within 6 hours of dosing. |
| Surgery |
Stop 14 days before scheduled surgery. Inform anesthesiologist. |
| Liver disease |
Caution. Choose a low-alcohol or alcohol-free option — consult our evaluating tincture quality guide. |
| Hops + estrogen-sensitive cancers |
Hops contains 8-prenylnaringenin, a phytoestrogen. Avoid if you have estrogen-receptor-positive breast cancer. |
| Common side effects |
Mild grogginess (under 10%), vivid dreams, dry mouth. Adjust dose timing earlier if grogginess persists. |
| Children |
Not for use under 12 years. Consult pediatrician for ages 12 to 17. |
| Other interactions |
See full sedative herb cautions guide. |
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Frequently Asked Questions
What tincture is best for sleep? +
For sleep onset, valerian-led formulas like Deep Sleep Tincture (2 mL, 30 to 60 minutes pre-bed) work for most adults. Across 16 RCTs (n=1,093) valerian shortened sleep latency by 15 to 20 minutes vs placebo. Pain-driven insomnia responds better to Jamaican dogwood; anxiety-driven insomnia to kava blends.
What is sleep tincture? +
A sleep tincture is a concentrated liquid herbal extract designed for sleep support, typically containing valerian, hops, passionflower, or related GABA-active herbs in a 40 to 50% alcohol base. A 2 mL sublingual dose taken 30 to 60 minutes before bed reaches the bloodstream within 5 to 15 minutes.
What are the best sleeping pills for diabetics? +
Speak with your physician — this is medical advice territory. Herbal sleep tinctures are generally considered safer than prescription Z-drugs for diabetics because they do not affect glucose. Avoid sleep formulas containing chromium, cinnamon, or fenugreek if you take metformin or insulin (additive hypoglycemic effect).
What is the most powerful herb for sleep? +
Jamaican dogwood is the most potent herbal sedative in regular monographs, working in 30 to 60 minutes at 1 to 2 mL doses. It is generally reserved for severe insomnia under practitioner guidance because of its strong sedative effect. For routine sleep support, valerian-based blends like Deep Sleep are gentler and more appropriate.
How fast does Deep Sleep Tincture work? +
Sublingual absorption begins within 5 to 15 minutes; subjective drowsiness typically appears at 30 to 45 minutes. Take 2 mL 30 to 60 minutes before lights-out for best timing. Most users notice sleep-onset improvement within 1 to 7 nights, with full effect at 2 to 4 weeks of consistent use.
Will I feel groggy in the morning? +
Most users do not. In 11 of 14 trials measuring next-day function, valerian showed no significant residual sedation. About 1 in 10 users report mild morning grogginess, which usually resolves by adjusting dose timing earlier (45 to 60 minutes before bed instead of right at lights-out).
Can I take it every night? +
Yes, with cycling. The standard protocol is 4 weeks on, 1 week off. Continuous valerian use beyond 6 weeks is well-tolerated in published trials but cycling prevents subjective tolerance some users report after 30 nights. Maximum continuous use without a break is 6 weeks.
Does it interact with melatonin? +
Mildly additive. You can combine 0.5 to 3 mg melatonin with 1 to 2 mL Deep Sleep Tincture for users who do not respond to either alone. Most users get adequate effect from the tincture alone — no melatonin needed. Higher melatonin doses (5+ mg) are not recommended in combination.
Is it safe during pregnancy? +
No. Valerian, hops, and passionflower all lack adequate pregnancy safety data, and the alcohol carrier is contraindicated. Avoid for the entire 40 weeks of pregnancy and during breastfeeding. Consult your OB about pregnancy-safe sleep options like magnesium glycinate (300 mg pre-bed).
Can I drink alcohol if I’m taking it? +
No within 6 hours of dosing. Alcohol amplifies sedation, can cause excessive drowsiness or impaired breathing during sleep, and increases risk of falls. Avoid all alcohol within 6 hours of taking the tincture. For occasional dinner-with-wine evenings, skip the tincture that night.
Can I take it with antidepressants? +
Talk to your prescriber. SSRIs and SNRIs have mild interaction risk with valerian and hops; tricyclic antidepressants and MAO inhibitors have higher interaction risk. Most users on standard SSRI doses tolerate Deep Sleep at 1 to 2 mL evening dose, but always consult your physician first.
What does it taste like? +
Valerian has a strong earthy, somewhat sweat-sock aroma that puts off some users. Sublingual hold for 30 seconds delivers the active compounds; you can then dilute the swallow in 2 to 4 oz of warm water or chamomile tea to mask the taste.
How long until I see results? +
Sleep onset improvement within 1 to 7 nights for most users. Sleep quality and continuity improvements over 2 to 4 weeks of consistent nightly use. About 1 in 5 users see no change in 14 nights — they are non-responders for the GABA-modulating approach and should explore other categories.
