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Amino acids are the building blocks of proteins; proteins play various roles in our body, such as energy production and muscle build-up. Leucine protein plays a key role in amino acid metabolism and is important for maintaining plasma and tissue pools. L-Leucine is a form of the amino acid Leucine.
L-Leucine, also known as 2-Amino-4-methylpentanoic acid, has a molecular weight that is a fundamental chemical property used in chemical characterization. L-Leucine belongs to the family of the Branched Chain Amino Acids, all used for muscle metabolism. L-Leucine is found naturally in foods that contain protein. Animal foods such as beef, chicken, eggs, and dairy, as well as other food sources like soybeans, lentils, and nuts, are rich in L-Leucine.
L-Leucine was discovered about 200 years ago, marking a milestone in biochemical research. Why not boost your muscle mass with Remedy’s Nutrition® L-Leucine Capsules
| Food Source | Category | Approx. L-Leucine Content |
|---|---|---|
| Whey Protein Isolate | Supplement / Dairy | ~3g per 30g scoop |
| Beef (Lean Steak) | Meat | ~2.5g per 100g (3.5 oz) |
| Chicken Breast | Poultry | ~2.2g per 100g (3.5 oz) |
| Tuna (Canned) | Fish | ~2.0g per 100g (3.5 oz) |
| Soybeans (Edamame) | Plant-Based | ~1.4g per 1 cup |
| Lentils (Cooked) | Plant-Based | ~1.3g per 1 cup |
| Eggs (Large) | Animal Product | ~0.6g per egg |
Muscle Growth and Recovery
L-Leucine is well-known for its role in stimulating muscle protein synthesis, which is essential for muscle growth and recovery after exercise. It also supports the maintenance of muscle proteins and may help prevent muscle loss, especially in muscle wasting conditions such as sarcopenia or after trauma.
Blood Sugar Management
L-Leucine may help regulate blood sugar levels by influencing insulin secretion and supporting glucose metabolism. Additionally, L-Leucine may help improve insulin sensitivity and promote glucose uptake in muscle and liver tissues.
Inflammation
L-Leucine has been shown to have anti-inflammatory properties, which may help reduce inflammation in the body. It also plays a role in regulating lipid metabolism and energy expenditure, which can impact body weight and fat loss.
Liver Support
L-Leucine may support liver health by promoting protein synthesis and aiding in the repair of liver tissue. It may also influence metabolic health in the context of high-fat diets and diet-induced obesity.
Exercise Performance and Muscle Mass or Strength
L-Leucine supplementation may support exercise performance and muscle mass or strength, though effects may depend on combined interventions such as resistance training.
L-Leucine otherwise known as 2-Amino-4-methylpentanoic acid, is found naturally in foods that contain protein and was discovered 200 years ago.
The effects of L-Leucine on body composition and strength were examined in the above-mentioned study. The test subjects were subjected to different protein compounds, including dietary leucine and leucine supplements, while undergoing resistance training and then examined.
Seventy-Five untrained, college-aged males.
Placebo, Whey protein concentrate, Whey protein hydrolysate, dietary leucine, and leucine supplements, twice daily
12 weeks
Precursor Skeletal muscle cell numbers were found to be higher in the group that took whey protein supplementation, which may lead to favorable outcomes over time.
While L-Leucine and leucine supplements can stimulate muscle protein synthesis, long-term supplementation alone may not significantly increase muscle mass or strength without concurrent resistance training.
L-Leucine is a powerhouse among essential amino acids, especially when it comes to supporting muscle health and overall metabolism. As a branched chain amino acid (BCAA), L-Leucine plays a pivotal role in activating muscle protein synthesis—the process your body uses to build and repair muscle tissue. This makes leucine supplementation a popular choice for those looking to increase muscle mass, enhance muscle growth, and speed up recovery after exercise.
| Function | Mechanism of Action | Primary Outcome |
|---|---|---|
| Muscle Protein Synthesis | Activates the mTOR signaling pathway, a master regulator of cell growth. | Promotes muscle repair, growth, and maintenance of lean body mass. |
| Glucose Metabolism | Stimulates insulin secretion from the pancreas and enhances glucose uptake in muscle cells. | Helps regulate blood sugar levels and supports stable energy. |
| Prevents Muscle Breakdown | Acts as an anti-catabolic agent, reducing the rate of muscle protein degradation. | Preserves muscle mass during periods of stress, caloric deficit, or inactivity. |
What sets L-Leucine apart from other amino acids is its unique ability to trigger the mTOR signaling pathway, a key regulator of protein synthesis in the body. By stimulating this pathway, L-Leucine helps your muscles use protein more efficiently, supporting both muscle strength and lean body mass. In addition to its muscle-building benefits, L-Leucine also plays a role in glucose metabolism, helping to regulate blood sugar levels and support healthy energy production.
Whether you’re an athlete, fitness enthusiast, or simply looking to maintain muscle mass as you age, L-Leucine is an essential amino acid that can make a significant difference in your health and performance. By incorporating L-Leucine into your dietary supplement routine, you’re giving your body the support it needs for optimal protein synthesis, muscle recovery, and metabolic health.
100% pure and high-quality L-Leucine supplement
60 vegan capsules (One Month Supply)
Free of fillers, additives, and preservatives
No gluten, yeast, corn, or dairy
Non-GMO
Handmade in Key Largo, FL, USA
Pharmacists reviewed and approved
Quality and potency are guaranteed
Manufactured in compliance with standards for dietary supplements
When you buy supplements from Remedy’s Nutrition®, you get the absolute best available. The best quality, the most beneficial products available anywhere, guaranteed! Remedy’s Nutrition® follows guidelines to regulate supplements for safety and quality. While the Food and Drug Administration oversees dietary supplement labeling, it does not regulate supplements as strictly as pharmaceuticals, so it is important to choose products from reputable companies that prioritize safety and quality.
High-quality leucine supplements, such as those from Remedy’s Nutrition®, can help support muscle recovery and metabolic health when used as directed.
The optimal dosage of Remedy’s Nutrition® L-Leucine depends on your individual health goals, activity level, and dietary needs. For most people aiming to support muscle protein synthesis and recovery, a daily intake of 2-5 grams of L-Leucine is considered effective. Some clinical nutrition studies have explored higher doses—up to 10 grams per day—for specific benefits such as improved glucose metabolism and enhanced protein synthesis.
It’s important to remember that everyone’s body is different, and factors like age, body weight, and overall protein intake can influence how much L-Leucine you need. Before starting any new dietary supplement, including L-Leucine, it’s wise to consult with a healthcare professional. They can help you determine the right dosage for your unique needs and ensure that your supplement routine is both safe and effective. Always follow the recommended dosage on the product label and consider starting with a lower dose to assess your body’s response.
By using L-Leucine as part of your daily routine, you can help maximize muscle protein synthesis, support healthy glucose metabolism, and give your body the building blocks it needs for optimal performance and recovery.
| Primary Goal | Recommended Dosage | Optimal Timing |
|---|---|---|
| Muscle Growth & Recovery | 2-5 grams per serving | Within 30 minutes after resistance exercise, ideally with protein. |
| Muscle Preservation (e.g., during dieting) | 2-5 grams per serving | Between meals or before fasted cardio to prevent muscle breakdown. |
| Blood Sugar Management | 2-5 grams per serving | With meals that contain carbohydrates to support glucose metabolism. |
| General Health & Sarcopenia Prevention | 2-5 grams per day | With any protein-containing meal to ensure adequate intake. |
Remedy’s Nutrition® L-Leucine Capsules can be taken with food or on an empty stomach. We do not add binders, fillers, or additives to our herbal supplements. Our supplements are easily digestible and the absorption is greatly improved over other inferior herbal supplements.
According to Dietary Reference Intakes established by authoritative organizations, how much leucine is recommended can vary depending on age, health condition, and individual needs. Leucine intake should be adjusted based on your specific health condition and age group to ensure optimal benefits and safety. High doses of leucine may lead to adverse effects, such as interference with nutrient metabolism or increased ammonia levels, so it is important not to exceed recommended amounts. Always consult a healthcare professional to determine how much leucine is appropriate for your particular health condition and to ensure your leucine intake aligns with current guidelines.
1000 mg per vegetarian capsule
One capsule daily
May be taken in the morning and/or evening
Feel free to contact us for a recommendation on how to take this supplement.
Nausea
Headache
Stomach Upset
Taking high doses of L-Leucine may increase the risk of side effects such as nausea, headache, or stomach upset.
Consult your physician for potential drug interactions before taking L-Leucine.
If you are currently taking diabetes medications, and medications for the thyroid.
Do not use L-Leucine during pregnancy and breast-feeding.
Consult your physician if you are scheduled for surgery.
While all the BCAAs are essential for muscle growth, especially leucine plays a key role in activating the mTOR pathway and promoting muscle protein synthesis. However, research shows that leucine is most effective when combined with other essential amino acids, as their presence enhances the anabolic effects on muscle tissue. Therefore, supplementing with L-Leucine alone may not be sufficient for optimal results.
Yes, L-Leucine can result in a higher testosterone level in the body.
Timing your L-Leucine supplementation can make a big difference in achieving your health and fitness goals. For those focused on muscle growth and recovery, taking Remedy’s Nutrition® L-Leucine Capsules after resistance exercise or with a protein-rich meal is ideal. This approach helps stimulate muscle protein synthesis when your body is most primed to rebuild and strengthen muscle tissue.
If your goal is to help regulate blood sugar, consider taking L-Leucine with meals that contain carbohydrates. This can support healthy glucose metabolism and help control blood sugar levels throughout the day. Some individuals also find benefits in taking L-Leucine before bedtime, as this may promote overnight muscle recovery and growth.
Ultimately, the best timing for your L-Leucine supplementation depends on your personal routine and health objectives. Consulting with a healthcare professional can help you develop a tailored plan that fits your lifestyle and maximizes the benefits of leucine supplementation. Whether you’re aiming for muscle recovery, improved protein synthesis, or better blood sugar regulation, L-Leucine can be a valuable addition to your dietary supplement regimen.
Daily, as an excellent post-workout, with some protein.
Whey Protein, Eggs, Beef, Chicken, Pork, and Tuna are great sources of dietary leucine, which is essential for maintaining adequate leucine intake and supporting muscle health. Foods high in leucine protein, especially animal foods like these, are particularly effective for meeting daily requirements and promoting muscle protein synthesis.
L-Leucine stimulates insulin release from the pancreas, which can enhance glucose uptake by promoting the movement of glucose into cells, thereby contributing to lower blood sugar levels. Additionally, L-Leucine can influence insulin sensitivity, with some studies suggesting that appropriate supplementation may improve insulin sensitivity and glucose metabolism. However, excessive intake of L-Leucine, especially in the context of obesity or nutrient overabundance, may activate pathways such as mTORC1 and S6K1, potentially leading to insulin resistance.
