Metabolism Power Pack

Studies and Trails for Metabolism Power Pack Components

Studies and Trials

"The Effect of a High-Dose Vitamin B Multivitamin Supplement on the Relationship between Brain Metabolism and Blood Biomarkers of Oxidative Stress: A Randomized Control Trial."

A diet rich in B-group vitamins is essential for optimal body and brain function, and insufficient amounts of such vitamins have been associated with higher levels of neural inflammation and oxidative stress, as marked by increased blood plasma homocysteine. Neural biomarkers of oxidative stress quantified through proton magnetic spectroscopy (1H-MRS) are not well understood, and the relationship between such neural and blood biomarkers is seldom studied.

The current study addresses this gap by investigating the direct effect of 6-month high-dose B-group vitamin supplementation on neural and blood biomarkers of metabolism.

• Randomized, double-blind, placebo-controlled design.
• 32 healthy adults (20 female, 12 male) aged 30“65 years underwent blood tests (vitamin B6, vitamin B12, folate, and homocysteine levels) and 1H-MRS of the posterior cingulate cortex (PCC) and dorsolateral prefrontal cortex (DLPFC) before and after supplementation.
• Results confirmed the supplement was effective in increasing vitamin B6 and vitamin B12 levels and reducing homocysteine, whereas there was no change in folate levels. There were significant relationships between vitamin B6 and N-acetylaspartate (NAA), choline, and creatine, as well as between vitamin B12 and creatine (ps < 0.05), whereas NAA in the PCC increased, albeit not significantly (p > 0.05).
• The results suggest the efficacy of high-dose B-group supplementation in reducing oxidative stress and inflammation through increasing oxidative metabolism. It may also promote myelination, cellular metabolism, and energy storage.

"Multivitamins and minerals modulate whole-body energy metabolism and cerebral blood-flow during cognitive task performance: a double-blind, randomised, placebo-controlled trial."

The brain is by far the most metabolically active organ in the body, with overall energy expenditure and local blood-supply closely related to neural activity. Both energy metabolism and cerebral vaso-dilation are dependent on adequate micronutrient status. This study investigated whether supplementation with ascending doses of multi-vitamin/minerals could modulate the metabolic and cerebral blood-flow consequences of performing cognitive tasks that varied in difficulty.

• Randomised, double-blind, placebo-controlled, parallel-groups study.
• 97 healthy females (25“49 y), received either placebo or one of two doses of multivitamins/minerals. Cerebral blood-flow (CBF) parameters in the frontal cortex, and total energy expenditure (TotalEnergy), carbohydrate and fat oxidation (CarbOxi/FatOxi), were measured during 5 tasks of graded cognitive difficulty and a control task (5 min per task) using Near-infrared spectroscopy (NIRS) and Indirect calorimetry of exhaled pulmonary gas (ICa) respectively. Assessments took place 60 min after the first dose and following eight weeks supplementation.
• During task performance supplementation with the first dose of micronutrients led to a dose-dependent increase in TotalEnergy and FatOxi throughout the post-dose assessment period following the higher dose, and increases in the total concentration of haemoglobin, a proxy measure for CBF, during task performance following the lower dose of vitamins/minerals (also containing coenzyme-Q10). Chronic supplementation over 8 weeks led to a dose-dependent increase in TotalEnergy during the task period. There were no interpretable effects on mood or cognitive performance.
• These results show that acute supplementation with micronutrients in healthy adults can modulate metabolic parameters and cerebral blood flow during cognitive task performance, and that the metabolic consequences are sustained during chronic supplementation. These findings suggest that both brain function and metabolism are amenable to micronutrient supplementation, even in adults who are assumed to have nutritional status typical of the population.

Remedy's Nutrition® Power Packs are better. Here's why:

• 100% pure and high-quality
• One month's supply
• Free of fillers, additives, and preservatives
• No gluten, yeast, corn, or dairy
• Non-GMO
• Vegan & Kosher
• Handmade in Key Largo the USA
• Pharmacists & Doctor formulated and approved
• Quality and potency are guaranteed

When you buy supplements from Remedy's Nutrition®, you get the absolute best available. The best quality, the most beneficial products available anywhere, guaranteed!

Remedy™s® Means Results! Quality, Purity, Pride.

Dosage

Power Surfer, Vitamin B-100 Complex

• 1000 mg per vegetarian capsule
• One capsule daily
• May be taken in the morning or evening

Adrenal Support

• 1000 mg per vegetarian capsule
• Two capsules daily
• May be taken in the morning and/or evening

Mega VMT

• 2000 mg per vegetarian capsule
• Two capsules daily
• May be taken in the morning and/or evening

Questions? Feel free to contact us for a recommendation on how to take these and other supplements.

Cautions

Potential Side Effects

Each product included in the Metabolism Power Pack may have potential side effects. Please, review the individual description of each product for a detailed list of side effects and cautions.

Drug interactions

Each product included in the Metabolism Power Pack may interact with certain medications. Consult your physician for potential drug interactions for each product.

Pregnancy and breast-feeding

Consult your physician before using the Metabolism Power Pack during pregnancy and breastfeeding.

Surgery

Consult your physician if you are scheduled for a surgery.

Other Cautions

Always consult with a healthcare practitioner before taking any new supplement.