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Yellow Dock Root Supplement Remedys Nutrition

Yellow Dock Root

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FAMILIAR NAME:

 Curled Dock, Curly Dock

SCIENTIFIC :

 Rumex Crispus

ORDER:

 Polygonaceae

PART USED:

 Leaves, Root

GROWN IN:

 Europe, Asia, North and South America, 

 

There has been extensive research done on Yellow Dock and it has been proven to be an effective liver detoxifier. It was one of the original eight ingredients in Essiak Tea and has demonstrated that it may have a positive effect on cellular toxicity.  (See studies below)  At Remedy's it plays an integral part in our Detox Tea, Liver Safeguard, and all products for skin and cellular issues. As always seek attention from you medical practitioner for liver and kidney issues to assure an accurate diagnosis.

Rumex L. species induce apoptosis in 1301, EOL-1 and H-9 cell lines.

Department of Pharmaceutical Botany, Medical University, Chodźki 1, 20-093 Lublin, Poland.

Abstract

The Rumex L. (dock) species for many centuries have been used in medical treatment, through their adstringent, spasmolitic or cholagogic action. In the present study, the in vitro screening of cytotoxic activities of ethanol extract from roots, leaves and fruits of six Rumex species: R. acetosa L., R. acetosella L., R. confertus Willd., R. crispus L., R. hydrolapathum Huds. and R. obtusifolius L. were performed. We found remarkable cytotoxic activities on leukemic 1301 and EOL-1 cell lines and T cell line at concentration dependent manners. Cytotoxic activity was determined in two ways: trypan blue test and annexin-V FITC and propidium iodide assay. Received IC50 values of investigated extracts on 1301, EOL-1 and H-9 cell lines ranged from 0.22, 0.17 and 0.04 to 2.56, 1.91 and 1.83 mg/mL, respectively. Analysis of morphological changes demonstrated that the extract exerted cell-death via apoptosis. The overall activities of Rumex species support the traditional use of the extract from the fruits of R. confertus, R. crispus, R. hydrolapathum and R. obtusifolius in the treatment of cancer.

PMID:  22594263    [PubMed - indexed for MEDLINE]

Antioxidant activity of Yellow Dock

Institute of Pharmacognosy, School of Pharmacy, University of Belgrade, Belgrade, Serbia.

Abstract

The methanol extract of ripe Rumex crispus L. fruits was evaluated for its antioxidant potential by assays for ferric-reducing antioxidant power (FRAP), DPPH-free radical scavenging activity (DPPH) and the influence on lipid peroxidation in liposomes (LP). Considerable activity was observed in all test systems (FRAP: 9.9 mmol Fe(2+) /g; DPPH IC(50) : 3.7 μg/mL; LP IC(50) : 4.9 μg/mL), comparable to that of BHT (FRAP: 8.0 μg/mL; DPPH IC(50) : 19.4 μg/mL; LP IC(50) : 3.5 μg/mL), but lower than the activity of ascorbic acid, rutin and quercetin, used as positive control substances. The in vivo effects were evaluated in several hepatic antioxidant systems (activities of LPx, GSH-Px, Px, CAT and XOD, as well as GSH content), after treatment with the studied yellow dock extract in different doses, or in combination with carbon tetrachloride (CCl(4) ). Pretreatment with the R. crispus extract inhibited CCl(4) -induced oxidative stress by decreasing LPx and increasing GSH content in a dose dependent manner, bringing the levels of antioxidant enzymes to near control values.

Copyright © 2010 John Wiley & Sons, Ltd.

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These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

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