White Willow Bark
$ 13.99 $ 15.99
Frequently Asked QuestionsWhat exactly is Remedy's Nutrition?
We're an Organic Vitamin & Supplement that offers the best dietary supplements on the market. We're a company that manufactures our own formulated supplements based on clinical studies and years of medical and dietary experience. We believe in providing the purest and most effective forms of supplementation that you an find. The majority of what we produce is organic, and we manufacture everything ourselves.What services do we provide?
We offer a variety of different services including: Weight Loss, Anti-Aging, Bio-Identical Hormones, Nutritional Consultations, Nursing Consultations, Tissue Testing (Hair Test), Natural Beauty Consultations, Professional Athlete Nutrition, Live Blood Analysis, Herbal Consultations, and Patient Evaluations.Who are we?
We are a group of Dietitians, Doctors, Nurses, and Herbalists who intrinsically believe in the power of nutrition, education, and maintaining only the highest of standards in dosages and quality for the past 42 years. Whilst being in the business for that long, one tends to learn a thing or two!
Willow, White Willow, Crack Willow, Purple Osier Willow
All Continents, except Australia and Antarctica
White Willow Bark is found in our Anti-Inflammatory, Headache Formulas, and others. It can act as a blood thinner so anyone taking medication that acts as blood thinner much check with your medical professional before taking this product. It has been show to be well tolerated and not to have the adverse affects that are found in aspirin. Recent research has attemplted to demonstrate its affect on tumor growth and thus fare the results seem to be positive. We will wait and see. Next time you get a headache, White Willow Bark just may be the key.
The use of willow bark dates back thousands of years, to the time of Hippocrates (400 BC) when patients were advised to chew on the bark to reduce fever and inflammation. Willow bark has been used throughout the centuries in China and Europe, and continues to be used today for the treatment of pain (particularly low back pain and osteoarthritis), headache, and inflammatory conditions, such as bursitis and tendinitis. The bark of white willow contains salicin, which is a chemical similar to aspirin (acetylsalicylic acid). In combination with the herb's powerful anti-inflammatory plant compounds (called flavonoids), salicin is thought to be responsible for the pain-relieving and anti-inflammatory effects of the herb. In fact, in the 1800s, salicin was used to develop aspirin. White willow appears to bring pain relief more slowly than aspirin, but its effects may last longer.
The willow family includes a number of different species of trees and shrubs native to Europe, Asia, and some parts of North America. Some of the more commonly known species are white willow/European willow (Salix alba), black willow/pussy willow (Salix nigra), crack willow (Salix fragilis), purple willow (Salix purpurea), and weeping willow (Salix babylonica). Not all willow species accumulate a therapeutically sufficient amount of salicin. In one study, the amount of salicin after 1 and 2 year growth in autumn and spring ranged from 0.08 - 12.6%. The willow bark sold in Europe and the United States usually includes a combination of the bark from white, purple, and crack willows.
Medicinal Uses and Indications
Willow bark is used to ease pain and reduce inflammation. Researchers believe that the chemical salicin, found in willow bark, is responsible for these effects. However, studies show several other components of willow bark, including plant chemicals called polyphenols and flavonoids, have antioxidant, fever reducing, antiseptic, and immune boosting properties. Some studies show willow is as effective as aspirin for reducing pain and inflammation (but not fever), and at a much lower dose. Scientists think that may be due to other compounds in the herb. More research is needed.
Studies suggest that willow bark may be useful for the following conditions:
Willow bark has been shown to relieve headaches. There is some evidence that it is less likely to cause gastrointestinal side effects than other pain relievers, such as ibuprofen (Advil) and other nonsteroidal anti-inflammatory drugs, do. However, studies have not shown this beyond all doubt, and people who are prone to stomach upset may want to avoid willow bark. Large-scale studies are needed to fully determine how safe and effective willow bark is for chronic or recurring headaches.
Low back pain
Willow bark appears to be effective for back pain. In a well-designed study of nearly 200 people with low back pain, those who received willow bark experienced a significant improvement in pain compared to those who received placebo. People who received higher doses of willow bark (240 mg salicin) had more significant pain relief than those who received low doses (120 mg salicin).
Several studies show that willow is more effective at reducing pain from osteoarthritis than placebo. In a small study of people with osteoarthritis of the neck or lower back, those who received willow bark experienced significant improvement in symptoms compared to those who received placebo. A similar study of 78 patients hospitalized with osteoarthritis of the knee or hip joint found that patients who received willow bark had significant pain relief compared to those who received placebo.
Professional herbalists may recommend willow bark for the following conditions, however, no scientific studies have shown that it works:
- Menstrual cramps
Dosage and Administration
Because of the danger of developing Reye syndrome (a rare but serious illness associated with the use of aspirin in children), children under the age of 16 should not take willow bark.
General dosing guidelines for willow bark are as follows:
- Dried herb (used to make tea): boil 1 - 2 tsp of dried bark in 8 oz of water and simmer for 10 - 15 minutes; let steep for ½ hour; drink 3 - 4 cups daily.
- Powdered herb (available in capsules) or liquid: 60 - 240 mg of standardized salicin per day; talk to your doctor before taking a higher dose.
- Tincture (1:5, 30% alcohol): 4 - 6 mL 3 times per day.
Because willow bark contains salicin, people who are allergic or sensitive to salicylates (such as aspirin) should not use willow bark. Some researchers suggest that people with asthma, diabetes, gout, gastritis, hemophilia, and stomach ulcers should also avoid willow bark. If you have any of these conditions, take nonsteroidal anti-inflammatory drugs (NSAIDs) regularly, or blood-thinning medication, ask your health care provider before taking willow bark. Children under the age of 16 should not take willow bark.
Side effects tend to be mild. However, stomach upset, ulcers, nausea, vomiting, and stomach bleeding are potential side effects of all compounds containing salicylates. Overdoses of willow bark may cause skin rash, stomach inflammation/irritation, nausea, vomiting, kidney inflammation, and tinnitus (ringing in the ears).
Pregnancy and Breastfeeding
Salicylates are not recommended during pregnancy, so pregnant and breastfeeding women should not take willow bark.
Interactions and Depletions
Because willow bark contains salicylates, it might interact with a number of drugs and herbs. Talk to your doctor before taking willow bark if you take any other medications, herbs, or supplements.
Willow bark may interact with any of the following:
Anticoagulants (blood-thinning medications) -- Willow bark may strengthen the effects of drugs and herbs with blood-thinning properties, and increase the risk of bleeding.
Beta blockers -- including Atenolol (Tenormin), Metoprolol (Lopressor, Toprol-XL), Propranolol (Inderal, Inderal LA). Willow bark may make these drugs less effective.
Diuretics (water pills) -- Willow bark may make these drugs less effective.
Nonsteroidal anti-inflammatory drugs -- including ibuprofen (Advil, Motrin) and naproxen (Aleve). Taking willow bark with these drugs may increase risk of stomach bleeding.
Methotrexate and phenytoin (Dilantin) -- Willow bark may increase levels of these drugs in the body, resulting in toxic levels.
Bisset NG. Herbal Drugs and Phytopharmaceuticals. Stuttgart, Germany: Medpharm Scientific Publishers; 2004:534-536.
Blumenthal M. The Complete German Commission E Monographs. Austin, Tex: American Botanical Council. Boston: Integrative Medicine Communications; 1998.
Chrubasik JE, Roufogalis BD, Chrubasik S. Evidence of effectiveness of herbal anti-inflammatory drugs in the treatment of painful osteoarthritis and chronic low back pain. Phytother Res. 2007 Jul;21(7):675-83. Review.
Chrubasik S. Pain therapy using herbal medicines [abstract]. Gynakologe. 2000;33(1):59-64.
Chrubasik S, Eisenburg E, Balan E, et al. Treatment of low back pain exacerbations with willow bark extract: a randomized double blind study. Am J Med. 2000;109:9-14.
Ernst E, Chrubasik S. Phyto-anti-inflammatories. A systematic review of randomized, placebo-controlled, double-blind trials. Rheum Dis Clin North Am. 2000;26(1):13-27.
Foster S, Duke JA. A Field Guide toMedicinal Plants and Herbs of the Eastern and Central US. Boston, Mass: Houghton Mifflin; 2000:321-323.
Freischmidt A, Jurgenliemk G, Kraus B, et al. Contribution of flavonoids and catechol to the reduction of ICAM-1 expression in endothelial cells by a standardised Willow bark extract. Phytomedicine. 2012;19(3-4):245-52.
Gagnier JJ, van Tulder M, Berman B, Bombardier C. Herbal medicine for low back pain. Cochrane Database Syst Rev. 2006;(2):CD004504.
Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm. 2000;57(13):1221-1227.
Hoffmann D. Therapeutic Herbalism. Santa Cruz, Calif: Therapeutic Herbalism Press; 2000.
Kenstaviciene P, Nenortiene P, Kiliuviene G, Zevzikovas A, Lukosius A, Kazlauskiene D. Application of high-performance liquid chromatography for research of salicin in bark of different varieties of Salix. Medicina. 2009;45(8):644-51.
Kuhn MA, Winston D. Herbal Therapy and Supplements. Philadelphia, Pa: Lippincott; 2001.
Little CV, Parsons T, Logan S. Herbal therapy for treating osteoarthritis. The Cochrane Library. 2002:1.
McGuffin M, Hobbs C, Upton R, et al, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, Fla: CRC Press; 1997:101.
Rakel: Integrative Medicine, 3rd. ed. Philadelphia, PA: Saunders Elsevier. 2012.
Schmid B, Ludtke R, Selbmann HK, et al. Efficacy and tolerability of a standardized willow bark extract in patients with osteoarthritis: randomized placebo-controlled, double blind clinical trial.Phytother Res. 2001 Jun;15(4):344-50.
Setty AR, Sigal LH. Herbal medications commonly used in the practice of rheumatology: mechanisms of action, efficacy, and side effects. Semin Arthritis Rheum. 2005 Jun;34(6):773-84.
Vlachojannis J, Magora F, Chrubasik S. Willow species and aspirin: different mechanism of actions. Phytother Res. 2011;25(7):1102-4.
Crack willow; European willow; Liu-zhi; Purple willow; Pussy willow; Salix alba; Salix nigra; Wheeping willow; White willow
- Last Reviewed on 02/14/2013
- Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network.
Source: Willow bark | University of Maryland Medical Center http://umm.edu/health/medical/altmed/herb/willow-bark#ixzz3Ev5Dc1U0
University of Maryland Medical Center
Salicin, an Extract from White Willow Bark, Inhibits Angiogenesis by Blocking the ROS-ERK Pathways.
Salicin has been studied as a potent antiinflammatory agent. Angiogenesis is an essential process for tumor progression, and negative regulation of angiogenesis provides a good strategy for antitumor therapy. However, the potential medicinal value of salicin on antitumorigenic and antiangiogenic effects remain unexplored. In this study, we examined the antitumorigenic and antiangiogenic activity of salicin and its underlying mechanism of action. Salicin suppressed the angiogenic activity of endothelial cells, such as migration, tube formation, and sprouting from an aorta. Moreover, salicin reduced reactive oxygen species production and activation of the extracellular signal-regulated kinase pathway. The expression of vascular endothelial growth factor was also decreased by salicin in endothelial cells. When the salicin was administered to mice, salicin inhibited tumor growth and angiogenesis in a mouse tumor model. Taken together, salicin targets the signaling pathways mediated by reactive oxygen species and extracellular signal-regulated kinase, providing new perspectives into a potent therapeutic agent for hypervascularized tumors. Copyright © 2014 John Wiley & Sons, Ltd.
Copyright © 2014 John Wiley & Sons, Ltd.
Phytother Res. 2014 Aug;28(8):1246-51. doi: 10.1002/ptr.5126. Epub 2014 Feb 17.