Inositol hexaphosphate (IP6) is considered a vitamin-like substance. It is also an anti-oxidant. IP6 is added to foods to prevent spoilage. IP6 is a component of high-fiber foods such as cereals, nuts, and legumes, but can be made in a laboratory. Other common name(s) include IP6, IP-6, InsP-6, inositol, phytic acid, phytate, myo-inositol hexaphosphate. Scientific/medical name(s): inositol-1,2,3,4,5,6-hexakisphosphate.
Mechanism of Action
The body converts these foods or supplements into compounds used to relay messages from the outside the cell to the cell nucleus. IP6 also helps in the metabolism of calcium and other minerals. Laboratory research on animals has revealed that IP6 may be effective in slowing the growth of tumors. For those undergoing chemotherapy, IP6 has been found to ease the effects of chemotherapy, resulting in improved quality of life.
IP6 is found mostly in nuts, cereals, and legumes. IP6 is considered effective for the prevention of kidney stones when consumed as part of the diet.
Pregnancy & breastfeeding: This supplement is considered safe when consumed in food amounts. Safety of larger food amounts is not known. Best safe practice is to limit to IP6 ingested in food while pregnant or breastfeeding.
Bleeding & Clotting disorders: Test tube study results seem to indicate that IP-6 can slow clotting of the blood, although this effect has not been shown in humans. Persons with clotting disorders or on blood-thinners should avoid IP6.
Anemia (Iron-deficiency): Because IP6 will bind with iron in the intestines, this can affect the amount of iron that a person can obtain from supplements or foods.
Bone disorders: Because IP6 can bind with calcium in the intestines, the amount of calcium a person can absorb from food or supplements may be affected. A reduction in calcium absorption can result in weaker bones. : IP-6 binds with calcium in the gastrointestinal (GI) tract. This reduces the amount of calcium that the body can absorb from food and supplements. Reduced calcium can affect bone strength.
For additional information and clinical studies on IP6, please visit our informational public service website at remedysnutrition.org.
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