What Is IP-6 & Inositol?
IP-6 & Inositol is a combination supplement pairing inositol, a sugar-alcohol cell messenger, with IP-6 (inositol hexaphosphate), its 6-phosphate antioxidant form. Remedy's formula delivers 1000 mg per vegan capsule, giving you both the insulin- and cycle-supporting inositol and the mineral-binding antioxidant IP-6 in a single daily capsule.
Supplement Facts
Serving size: 1 Vegan Capsule. Servings per container: 60.
| Amount Per Serving |
Amount |
% Daily Value |
| IP-6 |
340 mg |
* |
| Inositol |
110 mg |
* |
| Calcium Citrate |
210 mg |
* |
| Magnesium Glycinate |
340 mg |
* |
* Daily Value not established, as printed. That is not correct for calcium or magnesium, both of which have Daily Values.
Other ingredients: Cellulose, Glycerin, Water (vegan capsule)
Directions: One capsule daily.
Non-GMO, vegan, gluten free, no additives, no preservatives. Made in the USA.
Inositol is the form with the strongest research for women's metabolic and hormonal health, while IP-6 is studied mainly for antioxidant and cellular support. To understand how the two forms differ, see our guide to how IP-6 differs from plain inositol and what inositol is and its forms.
Once called vitamin B8, inositol is now considered a pseudovitamin because the body makes some of its own supply. Supplementing simply raises levels toward the 4-gram daily amounts used in clinical research, which food alone cannot provide since a typical diet supplies only about 1 gram per day.
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Forms: Inositol plus IP-6 (inositol hexaphosphate) combined
-
Dose: 1000 mg per single vegan capsule
-
Count: 60 capsules — a flexible 30 to 60-day supply
-
Free from: fillers, binders, gelatin, and common allergens
Why Choose Remedy's IP-6 & Inositol
Many inositol products force you to choose between a plain powder or a filler-packed capsule. Remedy's IP-6 & Inositol is a clean, vegan formula built for people who want a precise 1000 mg dose they can titrate toward research-backed targets.
| What You Get |
Why It Matters |
| 1000 mg inositol and IP-6 per capsule |
Precise 1-gram units make building to the 4-gram PCOS study dose simple |
| Vegan capsule |
No bovine or porcine gelatin, suitable for plant-based routines |
| No fillers or binders |
Clean label with nothing between you and the active nutrients |
| Made in the USA |
Produced in a facility following current good manufacturing practices |
IP-6 & Inositol Benefits: What Research Shows
Inositol has genuine clinical research behind it, especially for polycystic ovary syndrome, where meta-analyses report improved insulin sensitivity and ovulation.[1]Myo-Inositol Effects in PCOS: Meta-Analysis — Endocr Connect (2017) View source The table below summarizes the best-supported uses and the doses studied.
| Benefit Area |
Key Research Finding |
Dose Studied |
| PCOS and insulin |
Improved insulin sensitivity and lower androgens across pooled RCTs[2]Inositol(s) in Women With PCOS: Systematic Review — Int J Endocrinol (2016) View source
|
4 g/day, 40:1 ratio |
| Fertility and ovulation |
Supports ovarian response in PCOS assisted reproduction[3]Myo-Inositol in PCOS Assisted Reproduction — Reprod Health (2021) View source
|
4 g/day for 12 weeks |
| Mood and panic |
Reduced panic attacks in small double-blind trials[4]Inositol for Panic Disorder: Controlled Trial — Am J Psychiatry (1995) View source
|
12 to 18 g/day |
| Antioxidant support |
IP-6 binds iron and limits oxidative damage in lab studies[5]Phytate as an Antioxidant Against Iron Damage — Int J Mol Sci (2025) View source
|
1 to 2 g/day |
How IP-6 & Inositol Works
Inositol works as a second messenger, relaying signals from insulin and follicle-stimulating hormone inside your cells. When inositol is plentiful, cells respond to insulin more efficiently, which lowers the high insulin that drives excess androgens in PCOS.[6]Myo-Inositol in PCOS: Systematic Review of RCTs — Gynecol Endocrinol (2012) View source
IP-6 behaves differently: its 6 phosphate groups let it bind reactive metals like iron, which is the basis of its antioxidant reputation. During digestion the gut also frees some inositol from IP-6, so the two forms complement each other in one capsule.
This dual action is why a combined formula appeals to women who want both hormone-supporting inositol and everyday antioxidant coverage. Rather than taking two separate products, one 1000 mg capsule covers the metabolic messenger role and the mineral-binding antioxidant role at the same time.
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Inositol: Second messenger for insulin and ovarian signaling
-
IP-6: Binds iron and other metals as an antioxidant
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Together: Metabolic and antioxidant support in 1 capsule
Inositol for PCOS and Insulin
Inositol is the best-researched natural option for PCOS, targeting the insulin resistance behind roughly 70% of cases. Trials using 4 grams daily at a 40:1 ratio report lower fasting insulin, reduced free testosterone, and more regular ovulation over 3 to 6 months. Learn the full evidence in our guide to inositol for PCOS.
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Insulin: Fasting insulin and HOMA-IR fall in most trials
-
Androgens: Free testosterone drops over 12 weeks
-
Cycles: Ovulation returns for many within 3 months
Because it works with your own insulin signaling rather than forcing hormones, inositol tends to be gentle and easy to combine with other PCOS strategies. Many women find it a practical starting point before or alongside prescription options, always in partnership with their clinician.
Inositol for Fertility and Ovulation
For women trying to conceive with PCOS, inositol supports fertility mainly by restoring ovulation, the essential first step. Myo-inositol at 4 grams daily for 12 weeks is the researched protocol, and the 40:1 ratio helps protect egg quality. Read more in our guide to inositol for fertility and ovulation.
-
Ovulation: Returns in many PCOS women within 3 months
-
Egg quality: The 40:1 ratio avoids excess D-chiro
-
Honest view: It supports ovulation but never guarantees pregnancy
Inositol for Mood and Anxiety
Inositol has been studied for panic disorder and OCD at high doses of 12 to 18 grams daily, with a meta-analysis reporting a small overall benefit for anxiety.[7]Inositol for Depression and Anxiety: Meta-Analysis — Hum Psychopharmacol (2014) View source Evidence for depression is mixed, so we cover the honest picture in our guide to inositol for anxiety and mood.
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Panic: Fewer attacks in 2 small double-blind trials
-
OCD: Improved at 18 grams in 1 crossover study
-
Caution: Mood doses need medical supervision
IP-6 for Antioxidant and Cellular Support
IP-6 (inositol hexaphosphate), also called phytic acid, is the antioxidant partner in this formula. It works largely by chelating free iron that would otherwise drive oxidative damage, an effect shown in laboratory and preclinical research.[8]Bioavailability of Cereal Inositol Phosphates — Molecules (2025) View source
It is important to be honest here: IP-6's anticancer research is preclinical only, done in cells and animals, with no human clinical trials. Treat cellular-support claims as supportive wellness, not disease treatment.
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Iron binding: Chelates free iron that fuels radicals
-
Cellular support: Antioxidant activity in lab studies
-
Honest limit: 0 human cancer trials exist for IP-6
IP-6 & Inositol for Women
Women are the primary audience for inositol, since most research addresses PCOS, cycle regularity, and fertility. Beyond ovulation, better insulin sensitivity can ease the acne and unwanted hair linked to high androgens, making inositol a versatile daily choice for hormone-focused wellness.
Many women take inositol as a long-term foundation rather than a short course, because its benefits build with consistent daily use over 3 to 6 months. It also pairs well with the lifestyle basics that support hormone balance, including balanced meals, regular movement, and adequate sleep.
-
Cycles: More predictable periods reported within 3 months
-
Skin and hair: Lower androgens may ease acne over 12 weeks
-
Preconception: Often paired with 400 mcg folate
IP-6 & Inositol Dosage
Inositol dosing depends on your goal. For PCOS and fertility, 4 grams daily split into 2 doses is standard, while general wellness uses 1 to 2 grams. Because each capsule is 1000 mg, reaching a target is simple. Our guide to how to dose inositol covers timing and titration.
| Goal |
Daily Dose |
Timing |
| PCOS and metabolic |
4 g (4 capsules) |
2 morning, 2 evening, with food |
| Fertility and ovulation |
4 g (4 capsules) |
Split, for 12 weeks or more |
| General wellness |
1 to 2 g (1 to 2 capsules) |
Once daily with food |
| Antioxidant support |
1 to 2 g (1 to 2 capsules) |
Between meals |
Safety and Drug Interactions
Inositol is well tolerated, with mild nausea or loose stools appearing mostly above 12 grams daily. The interactions that matter involve diabetes medication and lithium, so review our detailed guide to inositol side effects and safety before combining it with prescriptions.
Important: If you take diabetes medication or lithium, or are pregnant, talk to your clinician before using inositol. High-dose inositol may add to glucose-lowering drugs and may oppose lithium therapy.
| Interaction |
Concern |
What to Do |
| Diabetes meds, insulin |
Additive blood-sugar lowering |
Monitor glucose for 2 weeks; consult prescriber |
| Lithium |
May blunt lithium's action |
Avoid high doses without psychiatric approval |
| Pregnancy |
Studied for GDM but individualized |
Only under OB or midwife guidance |
Frequently Asked Questions
What is IP-6 & Inositol used for? +
IP-6 & Inositol is used most for PCOS and cycle support, where inositol at 4 grams daily improves insulin sensitivity and ovulation. Inositol is also studied for fertility and anxiety, while the IP-6 portion adds antioxidant support. It combines both forms in a 1000 mg vegan capsule.
How many capsules should I take for PCOS? +
For PCOS, most research uses 4 grams of inositol daily, which is 4 capsules of this 1000 mg formula. Split them as 2 in the morning and 2 in the evening with food. Effects build over 3 to 6 months, so consistency matters more than any single dose.
Is inositol the same as IP-6? +
No. IP-6 is inositol bound to 6 phosphate groups, also called phytic acid, and is studied for antioxidant effects. Plain inositol is the free form with strong PCOS and fertility evidence. This product combines both, giving you the metabolic benefits of inositol and the antioxidant support of IP-6.
How long does inositol take to work? +
For PCOS, most trials report insulin and cycle changes at 8 to 12 weeks, with fuller effects by 3 to 6 months. Mood studies ran 4 to 6 weeks. Inositol is not a quick fix, so take it consistently for at least 12 weeks before judging your results.
Can inositol help me get pregnant? +
Inositol may help women with PCOS conceive by restoring ovulation, which often returns within 3 months on 4 grams daily. It does not guarantee pregnancy, and evidence outside PCOS is limited. Use it as ovulation support within a fertility plan guided by your clinician.
Is IP-6 & Inositol safe to take daily? +
Yes, inositol is well tolerated daily, with trials using 2 to 4 grams for 6 months or longer without serious effects. Mild nausea or loose stools can occur above 12 grams. People on diabetes or lithium medication, and pregnant women, should check with a clinician first.
Does inositol help with anxiety? +
Small double-blind trials found inositol at 12 to 18 grams daily eased panic disorder and OCD symptoms. However, depression add-on studies were negative. Evidence is preliminary and the doses are high, so inositol should support, not replace, professional mental-health care under supervision.
Can I take inositol with metformin? +
Inositol and metformin are sometimes combined for PCOS, and both lower insulin. Because their effects can add up, monitor your blood sugar for 2 weeks and involve your prescriber before combining them. A meta-analysis found the 2 produce similar metabolic benefits, with inositol causing fewer digestive side effects.
Does IP-6 treat cancer? +
No. IP-6 cancer research is preclinical only, done in cell and animal studies, with 0 human clinical trials proving it treats or prevents cancer. It should never replace conventional care. If you have cancer, discuss any supplement with your oncologist before considering IP-6 for any reason.
What is the best inositol ratio for PCOS? +
The 40:1 ratio of myo-inositol to D-chiro-inositol is the most researched and best mirrors healthy ovarian fluid. Products with too much D-chiro can harm egg quality. A 4-gram dose at 40:1 provides about 3.9 grams myo and 100 mg D-chiro, the split used in most modern trials.
Will inositol cause side effects? +
Side effects are uncommon at the 4-gram dose and mostly appear above 12 grams, including nausea, gas, and loose stools. Taking capsules with food and splitting the dose usually prevents them. Start at 1 to 2 grams and build up over 1 to 2 weeks to let your gut adapt.
Can men take IP-6 & Inositol? +
Yes, men can take it. While most research studies women with PCOS, inositol supports insulin signaling in everyone, and IP-6 offers antioxidant support regardless of sex. General-wellness doses are 1 to 2 grams daily. Men with diabetes should monitor blood sugar and consult a clinician first.
Should I take it with food? +
Taking inositol with food is not required but reduces nausea, especially in the first 1 to 2 weeks or at higher doses. For antioxidant IP-6 goals, some people prefer taking it between meals. If you notice stomach upset, pair each dose with a meal and split it further.
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