Alpha Lipoic Acid (ALA) 250 mg, 60 Vegan Capsules
- Powerful Antioxidant Support*
- Supports Healthy Blood Sugar Levels*
- Promotes Nerve Health & Energy*
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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Quick Answer: Alpha Lipoic Acid 250 mg
Alpha lipoic acid is a water-and-fat-soluble antioxidant clinically used for diabetic peripheral neuropathy, blood sugar regulation, and cellular oxidative stress. Take 1 capsule (250 mg) 1-2 times daily, 30 minutes before meals on an empty stomach. Benefits for nerve comfort typically appear within 4-12 weeks. Consult a doctor if diabetic or on thyroid medication.
What Is Alpha Lipoic Acid?
Alpha lipoic acid (ALA) is a naturally occurring compound your mitochondria produce in small amounts and use as a cofactor for energy metabolism. It is uniquely both water- and fat-soluble, which lets it reach every compartment of the cell — cytoplasm, mitochondria, and cell membrane. This "universal antioxidant" role explains why ALA is the most-studied supplement for diabetic nerve pain, with 600-1800 mg daily used in German clinical trials for over 30 years.
Remedy's Nutrition Alpha Lipoic Acid 250 mg delivers a flexible daily dose that can be split or combined to reach the therapeutic range used in clinical practice. One capsule is suitable for antioxidant baseline; 2-4 capsules split across the day covers neuropathy and blood sugar protocols.
Key Benefits
- Diabetic peripheral neuropathy. Clinical trials at 600-1800 mg daily show reduced burning, tingling, and numbness symptoms within 3-5 weeks.
- Blood sugar and insulin sensitivity. Research shows improved fasting glucose and A1c in people with type 2 diabetes at 300-600 mg daily.
- Universal antioxidant. Recycles vitamin C, vitamin E, glutathione, and CoQ10 — extending the life of other antioxidants.
- Liver support. Historically used in Germany for hepatic oxidative damage protection.
- Mitochondrial energy. Cofactor for pyruvate dehydrogenase, the gateway enzyme converting glucose into cellular ATP.
How to Use Alpha Lipoic Acid
Take on an empty stomach 30 minutes before meals — food (especially high-carb meals) reduces ALA absorption by 30-40%. Split larger doses across the day rather than taking all at once, because ALA's half-life is short (30-60 minutes).
| Goal | Daily Dose | Timing |
|---|---|---|
| General antioxidant baseline | 250 mg | Before breakfast, empty stomach |
| Blood sugar / insulin support | 300-600 mg | Split before 2 meals |
| Diabetic peripheral neuropathy | 600-1200 mg | Split across 2-3 pre-meal doses |
| Post-workout oxidative recovery | 250-500 mg | 30-60 min post-workout |
Take for at least 8-12 weeks before judging nerve effects. Mitochondrial and nerve changes build gradually — high doses do not speed up response, they just maintain therapeutic blood levels longer.
Key Ingredients
- Alpha Lipoic Acid 250 mg — pharmaceutical-grade racemic R/S form
- Vegan capsule shell — hypromellose (plant cellulose)
- No fillers, binders, or preservatives
- Free from gluten, dairy, soy, GMO
Who Benefits Most?
ALA is most researched in 4 groups:
- People with type 2 diabetes — for both blood sugar and neuropathy support
- Adults with peripheral nerve pain or tingling (confirmed or suspected neuropathy)
- Older adults — ALA levels decline with age and oxidative stress rises
- Athletes and high-intensity trainers — for post-workout oxidative recovery
Safety & Cautions
ALA is well tolerated at 250-600 mg daily. Mild stomach upset or skin rash are the most common side effects, usually resolved with lower starting doses or taking with water. Important interactions: ALA can lower blood sugar — diabetics on insulin or sulfonylureas should monitor closely and adjust medication with a provider. It may also affect thyroid hormone conversion, so people on levothyroxine should monitor TSH. Consult a provider before use if pregnant, breastfeeding, or undergoing chemotherapy (theoretical antioxidant interference). These statements have not been evaluated by the FDA; this product is not intended to diagnose, treat, cure, or prevent any disease.
Why Choose Remedy's Nutrition Alpha Lipoic Acid?
- Flexible 250 mg dose — suitable for baseline antioxidant or therapeutic stacking
- Vegan capsule — no gelatin, hypoallergenic
- Third-party tested for purity — no heavy metals or oxidative degradation
- Made in the USA in a cGMP-certified facility
- Pharmacist-formulated — clean label, no unnecessary additives
Frequently Asked Questions
What is alpha lipoic acid good for? +
Alpha lipoic acid is clinically used for diabetic peripheral neuropathy, blood sugar regulation, and antioxidant protection. German medical trials using 600-1800 mg daily show reduced nerve pain within 3-5 weeks. ALA is unique because it is both water- and fat-soluble, letting it protect every compartment of the cell. It also recycles other antioxidants including vitamin C, E, and glutathione.
How much alpha lipoic acid should I take daily? +
250 mg covers antioxidant baseline. Clinical protocols use 300-600 mg daily for blood sugar support and 600-1200 mg for diabetic peripheral neuropathy. Always split doses above 250 mg across the day because ALA has a short half-life of 30-60 minutes. Do not exceed 1800 mg daily. Take 30 minutes before meals on an empty stomach for best absorption.
Should I take alpha lipoic acid with food? +
No. ALA should be taken on an empty stomach — food reduces absorption by 30-40%, especially high-carbohydrate meals. Take it 30 minutes before breakfast, or between meals. If you experience mild stomach upset empty, take with just a small amount of water or a light snack. Never take with the actual meal you're dosing against.
Does alpha lipoic acid really help neuropathy? +
Yes. Multiple randomized trials — many from German clinics where ALA is a prescription medication — show 600-1800 mg daily reduces burning, tingling, and numbness in diabetic peripheral neuropathy within 3-5 weeks. Effects build over 8-12 weeks. IV ALA shows faster relief, but oral is effective for maintenance and earlier-stage neuropathy at adequate dose.
What are the side effects of alpha lipoic acid? +
ALA is generally well tolerated. The most common side effects are mild stomach upset, nausea, and occasional skin rash — all usually resolved with lower doses or water. A rare but serious note: ALA can lower blood sugar, which matters for people on diabetes medications. Monitor glucose closely when starting. Insulin or sulfonylurea doses may need adjustment with provider guidance.
Can I take alpha lipoic acid with diabetes medications? +
Only with provider supervision. ALA has a blood-sugar-lowering effect that can stack with insulin, sulfonylureas (glyburide, glipizide), and metformin. This is often therapeutically desirable, but dose adjustments are needed to prevent hypoglycemia. Start at 250 mg, monitor glucose closely for 2 weeks, and involve your diabetes provider in any dose changes. Never stop prescribed medications to take ALA alone.
How long until alpha lipoic acid works? +
3-12 weeks depending on goal. Nerve pain relief typically begins at 3-5 weeks with adequate dose (600+ mg/day). Blood sugar and A1c changes show on lab tests at 8-12 weeks. Antioxidant and general energy effects are less measurable but cumulative. Consistency at the right dose matters more than high single doses — ALA's short half-life makes divided dosing essential.
R-ALA vs alpha lipoic acid — which is better? +
Our product is racemic R/S ALA, the form used in the majority of clinical trials. R-ALA is the naturally occurring isomer, absorbed slightly better than the S form. For most people, standard ALA at adequate dose (300-600 mg) delivers the same clinical benefit as R-ALA at half the cost. If using R-ALA specifically, typical dose is 50-60% of racemic dose.